Global patient safety and antiretroviral drug-drug interactions in the resource-limited setting
نویسندگان
چکیده
منابع مشابه
Drug interactions involving combination antiretroviral therapy and other anti-infective agents: repercussions for resource-limited countries.
The scale-up of antiretroviral treatment (ART) in resource-poor countries has been impressive, both in its scope and in its impact. In 2003, 400,000 people in resource-limited settings were receiving antiretroviral drugs (ARVs); by 2006, this number had increased to 2 million people [1]. Treatment of common infections occurring with HIV is also increasing, as most HIV-infected persons live in a...
متن کاملEmerging antiretroviral drug interactions.
With HIV-infected patients living longer and recommendations to initiate antiretrovirals (ARVs) being made earlier, the likelihood for potential drug-drug interactions between ARVs and concurrent medications used to manage co-morbid conditions will increase. In order to maximize the clinical benefit and minimize potential toxicity of ARVs and co-administered medications, it is important for cli...
متن کاملTherapeutic drug monitoring and drug-drug interactions involving antiretroviral drugs.
The consensus of current international guidelines for the treatment of HIV infection is that data on therapeutic drug monitoring (TDM) of non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (Pls) provide a framework for the implementation of TDM in certain defined scenarios in clinical practice. However, the utility of TDM is considered to be on an individual basis ...
متن کاملDrug-drug interactions with newer antiretroviral agents.
Knowledge of drug interactions among antiretroviral agents and other drugs used by HIV-infected patients is essential to maintaining safety and efficacy of drug treatment. Often, the clinical impact of drug-drug interactions cannot be predicted on the basis of pharmacokinetic interactions alone, highlighting the need for studies and analyses that provide exposure-response data. Drug interaction...
متن کاملSignificant drug interactions in dermatology
Systemic drugs have been used widely in the treatment of many skin diseases. Although dermatologists are familiar with the guidelines of selecting appropriate patients and prescribing systemic drugs, their knowledge about the side effects and significant interactions of systemic drugs used in dermatology is more limited. So a short review on important drug interactions seems to be useful. Some ...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2012
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dks346